Translational Research Program

DEFINITION OF TRANSLATIONAL RESEARCH

COMMITTEE MEMBERS

Marc Jeschke – P/S Chair T/R committee
Michael Fehlings – N/S VC Research and VC T/R committee
James Rutka –N/S - Ad Hoc
Margarete Akens – TECHNA-UHN O/S – Research
Leo da Costa – N/S
Peter Dirks – N/S
Mark Erwin – N/S – Research
Tom Forbes – V/S
Boris Hinz – G/S – Research
Osami Honjo – C/S
Shaf Keshavjee – T/S
Cindi Morshead – Anatomy – Research
Taufik Valiante – N/S
Albert Yee – O/S
Augusto Zani – G/S 
Joseph Ferenbok – Director, TRP – UoT – Ad Hoc
Uri Tabori – Oncologist, Haematology/Oncology, Sick Kids – Ad Hoc

Marc Jeschke

Marc Jeschke, MD, PhD, FACS, FCCM, FRCS(C)
Chair, Translational Research, Department of Surgery, University of Toronto
Email: marc.jeschke@sunnybrook.ca

Affiliation: Professor, Division of Plastic Surgery, Departments of Immunology and Surgery, University of Toronto; Chair, Burn Research, Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre; Senior Scientist, Sunnybrook Research Institute, Toronto, ON

Research Interests: Regenerative medicine, skin printing and metabolic research, mainly translational

PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=Jeschke+M

Margarete Akens

Margarete Akens, PhD

Email: margarete.akens@rmp.uhn.ca

 

Affiliation: Techna Institute, University Health Network; Assistant Professor, Departments of Medical Biophysics and Surgery, University of Toronto, Toronto, ON

 

Research Interests: pre-clinical model of bone-related cancer, photodynamic therapy, radiation, comparative oncology

PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=akens

Leodante da Costa

Leodante da Costa, MD|
Email: leo.dacosta@sunnybrook.ca

Affiliation: Cerebrovascular and Endovascular Neurosurgery, Associate Professor, Neurosurgery and Medical Imaging, Sunnybrook Hospital, and University of Toronto, Toronto, ON

Research Interests: My interest in clinical research is centered around the development of advanced imaging modalities to evaluate neuronal function and monitor cerebral blood flow mechanisms and their change in health and disease. The main areas of investigation currently are traumatic brain injury and subarachnoid hemorrhage (SAH) after intracranial aneurysm rupture, aiming to understand how these brain injuries may affect function and how the changes induced by it can lead to secondary injury, affect outcome, and to identify an optimal window for intervention.

PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed?term=(((((((Da%20Costa%2C%20Leodante%5BAuthor%5D)%20OR%20Da%20Costa%2C%20Leodante%20B%5BAuthor%5D)%20OR%20Da%20Costa%2C%20Leodante%20Batista%5BAuthor%5D)%20OR%20Da%20Costa%2C%20Leodante%20Batista%20JR%5BAuthor%5D)%20OR%20Da%20Costa%2C%20Leodante%20JR%5BAuthor%5D))%20OR%20Dacosta%2C%20Leodante%5BAuthor%5D)%20OR%20da%20costa%2C%20leo%5BAuthor%5D

Peter Dirks

Peter Dirks, MD, PhD, FRCSC
Email: peter.dirks@sickkids.ca

Affiliation: Professor, Division of Neurosurgery, Department of Surgery, University of Toronto; Division of Neurosurgery, Developmental & Stem Cell Biology, The Hospital for Sick Children, Toronto, ON  

Research Interests: Vascular & neoplastic diseases of the nervous system, stem cells & cell cycle pathways

PubMed Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=the+university+of+toronto+AND+peter+dirks

Mark Erwin

W. Mark Erwin, DC, PhD
Email: mark.erwin@utoronto.ca

Affiliation: Assistant Professor, Divisions of Neurological and Orthopaedic Surgery, Department of Surgery, University of Toronto; Chief Science Officer, Notogen Inc., Toronto, ON
Research Interests: Degenerative Disc Disease, regenerative medicine, stem cells, recombinant proteins, translational research
Pub Med Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=Erwin+WM+%5Bau%5D

Michael G. Fehlings

Michael G. Fehlings, MD, PhD, FRCSC, FACS

Email: michael.fehlings@uhn.ca

 

Affiliation: Vice Chair Research, Department of Surgery; Professor of Neurosurgery, Gerald & Tootsie Halbert Chair in Neural Repair & Regeneration; Co-Chairman Spinal Program, University of Toronto; Toronto Western Hospital, University Health Network, Toronto, ON

Research Interests: Spinal cord injury, CNS injury, neural repair, neuroprotection, regeneration, stem cells, clinical trials, imaging, electrophysiology, translational neuroscience research

PubMed Link: http://www.ncbi.nlm.nih.gov/pubmed?cmd=PureSearch&term=(Fehlings M[au] OR 9168289[uid])

Joseph Ferenbok

Affiliation: Director, Translational Research Program in Health Science, Institute of Medical Science; Assistant Professor, Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, ON http://trp.utoronto.ca/

Thomas L. Forbes

Thomas L. Forbes, MD, FRCSC, FACS
Email: Thomas.Forbes@uhn.ca

Affiliation: R. Fraser Elliott Chair & Division Head, University Health Network; Professor & Chair, Division of Vascular Surgery, Department of Surgery, University of Toronto, Toronto, ON
Research Interests: Clinical outcomes, medical devices, complex aortic aneurysms and spinal cord complications
PubMed Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=forbes+tl

Boris Hinz

Boris Hinz, PhD
Email: boris.hinz@utoronto.ca

Affiliation: Professor, Laboratory of Tissue Repair and Regeneration, Faculty of Dentistry, University of Toronto, Room 457, 123 Edward Street, Toronto, ON
http://hinzlab.com/
Research Interests: Fibrosis, wound healing, tissue repair, myofibroblast, scarring, cell contraction, tissue contracture, cytoskeleton, cell adhesion, integrins, transforming growth factor, extracellular matrix, fibroblast, inflammation, mechanics
PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=boris+hinz

 

Osami Honjo

Osami Honjo, MD, PhD
Email: osami.honjo@sickkids.ca

Affiliation: Interim Head, Division of Cardiovascular Surgery, The Hospital for Sick Children; Senior Associate Scientist, Translational Medicine; Surgical Director, Heart Transplantation and Mechanical Circulatory Support; Medical Co-Director, Hospital Tissue Bank; Associate Professor, Department of Surgery, University of Toronto, Toronto, ON
Research Interests: ex-vivo heart perfusion, mechanical assist for single ventricle physiology, neonatal cardiac surgery, single ventricle palliation
PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed

Shaf Keshavjee

Shaf Keshavjee, MD, MSc, FRCSC, FACS

Email: shaf.keshavjee@uhn.ca

 

Affiliation: Professor, Division of Thoracic Surgery & Institute of Biomaterials and Biomedical Engineering, Vice Chair Innovation, Department of Surgery, University of Toronto; Surgeon-in-Chief, Sprott Department of Surgery, James Wallace McCutcheon Chair in Surgery, Director, Toronto Lung Transplant Program, Director, Latner Thoracic Research Laboratories, University Health Network, Toronto, ON

Research Interests: Lung transplantation, ex vivo lung perfusion, acute & chronic lung injury, lung therapeutics, diagnostics, clinical translational

PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=keshavjee+s+toronto

Cindi Morshead

Cindi M. Morshead, PhD
Email: cindi.morshead@utoronto.ca

Affiliation: Professor and Chair, Division of Anatomy, Department of Surgery; Rehabilitation Sciences Institute, Institute of Biomaterials and Biomedical Engineering, Toronto Rehabilitation Institute, The Donnelly Centre, University of Toronto,
Toronto, ON

Research Interests: Dr. Morshead's expertise is in stem cell biology and specifically, in the field of adult neural stem cells and their role in regenerative medicine strategies. Her team is actively pursuing the role of stem cells in models of injury such as stroke, cerebral palsy, acquired brain injury and spinal cord injury. Her work encompasses a variety of in vitro and in vivo paradigms to promote neural repair including activate endogenous neural precursor cells using durgs, electric field application as well as cell transplantation and cellular reprogramming.
www.thedonnellycentre.utoronto.ca
http://morsheadlab.technology/

PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=Cindi+Morshead

James Rutka

James T. Rutka, OC, O Ont, MD, PhD, FRCSC, FACS, FAANS

Email: james.rutka@sickkids.ca

Affiliation: RS McLaughlin Professor and Chair, Department of Surgery, University of Toronto; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON

Research Interests: Brain tumours, molecular biology, translational research, invasion, genetics

PubMed Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=the+university+of+toronto+AND+james+rutka

Uri Tabori

Affiliation: Staff Haematologist/Oncologist, Division of Haematology/Oncology; Senior Scientist, Research Institute and The Arthur & Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children. Professor of Paediatrics and Medical Biophysics, University of Toronto, Toronto, ON
Research Interests: research program is focused on combining biological and translational research in pediatric oncology. Specifically, we are interested in studying mechanisms underlying brain tumor immortality and recurrence in the context of predisposition to cancer. Currently our group is studying 3 major areas related to this concept: The role of replication repair deficiency and hypermutation in childhood cancer. Mechanisms of growth arrest in gliomas and telomere biology in cancer.
PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed?cmd=PureSearch&term=tabori+u%5BAuthor%5D

Taufik Valiante

Taufik A. Valiante, MD, PhD, FRCSC
Email: Taufik.Valiante@uhn.caAffiliation: Associate Professor Neurosurgery, Department of Surgery, University of Toronto; Cross-Appts to Institute of Biomaterials and Biomedical Engineering & Electrical and Computer Engineering; Scientist Krembil Research Institute; Director Surgical Epilepsy Program; Co-Director CRANIA (CenteR for Advancing Technological Innovation to Application)
Research Interests: computational neuroscience, neuromodulation, cognition, post-surgery
outcomes

Pubmed Linkhttps://www.ncbi.nlm.nih.gov/myncbi/browse/collection/49370478/?sort=date&direction=descending

Albert J.M. Yee

Albert J.M. Yee, MD, MSc, FRCSC, DABOS

Email: Albert.Yee@sunnybrook.ca

 

Affiliation: Holland Bone & Joint Program Chief and the Head of the Division of Orthopaedic Surgery, Sunnybrook Health Sciences Centre; Consultant in Surgical Oncology, Odette Cancer Centre; Professor of Surgery, Division of Orthopaedic Surgery, Department of Surgery, University of Toronto; Co-Director, University of Toronto Department of Surgery Spine Program; Vice-Chair Research, Division of Orthopaedic Surgery, University of Toronto; Co-Chair, Bone & Joint Canada; Associate Scientist, Sunnybrook Research Institute, Toronto, ON

Research Interests: cancer metastases to bone, translational vertebral metastasis research, spine surgery education

PubMed Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=YeeAJ[Author]&cauthor=true&cauthor_uid=25648441

Augusto Zani

Affiliation: Assistant Professor, Division of General and Thoracic Surgery, Department of Surgery, University of Toronto; Developmental & Stem Cell Biology, The Hospital for Sick Children, Toronto, ON
Research Interests: regenerative medicine, stem cell therapy, extracellular vesicles, fetal lung development, congenital diaphragmatic hernia, necrotizing enterocolitis, neonatal surgery, outcome research in pediatric surgery
PubMed Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=zani+a

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