Dr. Darlene Fenech completed medical school in Hamilton at McMaster University and General Surgery residency at the University of Calgary. Following residency, she completed a fellowship in colorectal surgery at the University of Toronto. During her fellowship, she completed a Masters of Clinical Epidemiology. 

Presently, she is a colorectal surgeon the Odette Cancer Centre, with a clinical interest in laparoscopic colorectal surgery, and locally advanced colorectal cancer. Her academic interests include quality improvement initiatives and undergraduate education.